Friday, September 17, 2010

ISI Web of Knowledge Alert - Thompson, P

ISI Web of Knowledge Citation Alert

Cited Article: Thompson, P. A general boundary condition for liquid flow at solid surfaces
Alert Expires: 09 NOV 2010
Number of Citing Articles: 1 new records this week (1 in this e-mail)
Organization ID: 3b97d1bbc1878baed0ab183d8b03130b
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Title:
Detection of C-Reactive Protein in Evanescent Wave Field Using Microparticle-Tracking Velocimetry

Authors:
Fan, YJ; Sheen, HJ; Liu, YH; Tsai, JF; Wu, TH; Wu, KC; Lin, SM

Author Full Names:
Fan, Yu-Jui; Sheen, Horn-Jiunn; Liu, Yi-Hsing; Tsai, Jing-Fa; Wu, Tzu-Heng; Wu, Kuang-Chong; Lin, Shiming

Source:
LANGMUIR 26 (17): 13751-13754 SEP 7 2010

Language:
English

Document Type:
Article

KeyWords Plus:
REFLECTION FLUORESCENCE MICROSCOPY; SLOW VISCOUS MOTION; SPHERE PARALLEL; PLANE WALL; FLOW; NANOPARTICLES; IMMUNOSENSOR; ILLUMINATION; SURFACE

Abstract:
A new technique is developed to measure the nanoparticles' Brownian motions by employing microparticle-tracking velocimetry (micro-PTV) in evanescent wave field, which can provide high signal-to-noise ratio images for analyzing nanoparticles. movements. This method enables real-time detection of C-reactive proteins (CRPs) during the rapid interaction between CRPs and anti-CRP-coated nanobeads as CRP concentrations are related to the nanobeads' Brownian velocity in the equilibrium state. The smallest observable nanobeads with 185 nm were utilized in this experiment to detect CRP concentrations as low as 0.1 mu g/mL. even in a high-viscosity solution. Further, the dissociation constant, K-D, can be evaluated based on the experimental results.

Reprint Address:
Sheen, HJ, Natl Taiwan Univ, Inst Appl Mech, Taipei 106, Taiwan.

Research Institution addresses:
[Fan, Yu-Jui; Sheen, Horn-Jiunn; Wu, Tzu-Heng; Wu, Kuang-Chong; Lin, Shiming] Natl Taiwan Univ, Inst Appl Mech, Taipei 106, Taiwan; [Lin, Shiming] Natl Taiwan Univ, Ctr Optoelect Biomed, Taipei 106, Taiwan

E-mail Address:
sheenh@ntu.edu.tw

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Cited Reference Count:
26

Times Cited:
0

Publisher:
AMER CHEMICAL SOC; 1155 16TH ST, NW, WASHINGTON, DC 20036 USA

Subject Category:
Chemistry, Multidisciplinary; Chemistry, Physical; Materials Science, Multidisciplinary

ISSN:
0743-7463

DOI:
10.1021/la102137j

IDS Number:
644DX

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